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2. | | LOBAK, T.; PASINI, A.; OLIVEIRA, H. C.; FRACETO, L. F.; ROGGIA, S. Atividade inseticida de nanoformulação à base de azadiractina sobre Anticarsia gemmatalis (Lepidoptera: Erebidae). In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 27.; CONGRESSO LATINO-AMERICANO DE ENTOMOLOGIA, 10., 2018, Gramado, RS. Saúde, ambiente e agricultura: anais. Santo Antonio de Goiás: SEB: UFSM, 2018. v. 2. resumo. p. 1650. Biblioteca(s): Embrapa Soja. |
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7. | | CLEMENTE, Z.; CASTRO, V. L. S. S. de; JONSSON, C. M.; FRACETO, L. F. Exposição subletal de Daphnia a anatase provoca alterações bioquímicas dependentes da condição de iluminação. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 8., 2014, Juiz de Fora. Anais... São Carlos, SP: Embrapa Instrumentação; Campo Grande, MS: Embrapa Gado de Corte; Juiz de Fora: Embrapa Gado de Leite, 2014. p. 558-562. Biblioteca(s): Embrapa Meio Ambiente. |
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8. | | CLEMENTE, Z.; CASTRO, V. L. S. S. de; JONSSON, C. M.; FRACETO, L. F. Toxicity of nano-TiO2 in fish - an overview of environmental impact scenario. In: INTERNATIONAL CONFERENCE ON FOOD AND AGRICULTURE APPLICATIONS OF NANOTECHNOLOGIES - NanoAgri, 2010, São Pedro, SP. [Anais...] São Pedro: Aptor Software, 2010. 1 CD-ROM. Editors: Caue Ribeiro, Odílio Benedito Garrido de Assis, Luiz Henrique Capparelli Mattoso, Sérgio Mascarenhas. Biblioteca(s): Embrapa Meio Ambiente. |
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9. | | YAMAWAKI, P. C.; TEIXEIRA, E. M.; CORREA, A. C.; MATTOSO, L. H. C.; FRACETO, L. F.; LIMA, R. de. Análises de genotoxicidade de nanofibras celulósicas por teste do allium cepa. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 6., 2012, Fortaleza. Anais... São Carlos: Embrapa Instrumentação; Fortaleza: Embrapa Agroindústria Tropical, 2012. p. 473-475. Editores: Maria Alice Martins, MOrsyleide de Freitas Rosa, Men de Sá Moreira de Souza Filho, Nicodemos Moreira dos Santos Junior, Odílio Benedito Garrido de Assis, Caue Ribeiro, Luiz Henrique Capparelli Mattoso. Biblioteca(s): Embrapa Instrumentação. |
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10. | | MOURA, N. M. de; LIMA, R. de; FEITOSA, L.; AOUADA, F. A.; FRACETO, L. F.; MATTOSO, L. H. C. Análise genotóxica de nanopartículas poliméricas de quitosana/ácido polimetacrilico com diferentes tamanhos. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 5., 2009, São Carlos. Anais... São Carlos: Embrapa Instrumentação Agropecuária, 2009. p. 207-209. Editado por Odílio Benedito Garrido de Assis; Wilson Tadeu Lopes da Silva; Luiz Henrique Capparelli Mattoso. Biblioteca(s): Embrapa Instrumentação. |
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11. | | MARUYAMA, C. R.; TEIXEIRA, E. M.; CORRÊA, A. C.; MATTOSO, L. H. C.; LIMA, R.; FRACETO, L. F. Avaliação da genotoxicidade das nanofibras, com a utilização do teste cometa. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 6., 2012, Fortaleza. Anais... São Carlos: Embrapa Instrumentação; Fortaleza: Embrapa Agroindústria Tropical, 2012. p. 476-478. Editores: Maria Alice Martins, MOrsyleide de Freitas Rosa, Men de Sá Moreira de Souza Filho, Nicodemos Moreira dos Santos Junior, Odílio Benedito Garrido de Assis, Caue Ribeiro, Luiz Henrique Capparelli Mattoso. Biblioteca(s): Embrapa Instrumentação. |
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14. | | GRILLO, R.; CLEMENTE, Z.; JONSSON, C. M.; SANTOS, N. Z. P.; FEITOSA, L. O.; LIMA, R.; FRACETO, L. F. Evaluation of the toxicity of poly (E-Caprolactone) nanocapsules containing triazine herbicides. In: SOUTH-AMERICAN SYMPOSIUM ON MICROENCAPSULATION, 2012, Limeira/Brasil. Limeira/Brasil: Bioencapsulation Research Group, 2012. Biblioteca(s): Embrapa Meio Ambiente. |
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15. | | LIMA, R.; FEITOSA, L.; PEREIRA, A. E. S.; MOURA, M. R. de; MATTOSO, L. H. C.; FRACETO, L. F. Genotoxicity of chitosan nanoparticles with different compositions for use in food packaging In: INTERNATIONAL CONFERENCE ON FOOD AND AGRICULTURE APPLICATIONS OF NANOTECHNOLOGIES - NanoAgri, 2010, São Pedro, SP. [Anais…] São Pedro: Aptor Software, 2010. Editors: Caue Ribeiro, Odílio Benedito Garrido de Assis, Luiz Henrique Capparelli Mattoso, Sérgio Mascarenhas. Biblioteca(s): Embrapa Instrumentação. |
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16. | | ALBUQUERQUE, F. P. de; PREISLER, A. C.; FRACETO, L. F.; OLIVEIRA, H. C.; CASTRO, V. L. S. S. de. Overview of nanopesticide environmental safety aspects and regulatory issues: the case of nanoatrazine. In: FRACETO, L. F.; CASTRO, V. L. S. S. de; GRILLO, R.; ÁVILA, D.; OLIVEIRA, H. C.; LIMA, R. de (Ed.). Nanopesticides: from research and development to mechanisms of action and sustainable use in agriculture. Cham: Springer, 2020. p. 281-298. Biblioteca(s): Embrapa Meio Ambiente. |
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18. | | CLEMENTE, Z.; CASTRO, V. L. S. S. de; FEITOSA, L. O.; LIMA, R.; JONSSON, C. M.; MAIA, A. de H. N.; FRACETO, L. F. Acute exposure of fish to nano-TiO2 at environmental levels of ultraviolet light. In: THE BRITISH TOXICOLOGY SOCIETY SPRING CONGRESS, 2013, Birmingham. Abstracts... Birmingham: The British Toxicology Society, 2013. Ref. P004. Biblioteca(s): Embrapa Meio Ambiente. |
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19. | | BARGA, M. de A.; SANTOS, M. F. da S.; TEIXEIRA, E. M.; CORRÊA, A. C.; MATTOSO, L. H. C.; FRACETO, L. F.; LIMA, R. de. Avaliação genotoxica de nanofibras - citogenética. In: WORKSHOP DA REDE DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 6., 2012, Fortaleza. Anais... São Carlos: Embrapa Instrumentação; Fortaleza: Embrapa Agroindústria Tropical, 2012. p. 479-481. Editores: Maria Alice Martins, MOrsyleide de Freitas Rosa, Men de Sá Moreira de Souza Filho, Nicodemos Moreira dos Santos Junior, Odílio Benedito Garrido de Assis, Caue Ribeiro, Luiz Henrique Capparelli Mattoso. Biblioteca(s): Embrapa Instrumentação. |
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20. | | CLEMENTE, Z.; CASTRO, V. L. S. S. de; FEITOSA, L. O.; LIMA, R.; JONSSON, C. M.; MAIA, A. de H. N.; FRACETO, L. F. Biomarker evaluation in fish after prolonged exposure to nano-TiO2: influence of illumination conditions and crystal phase. Journal of Nanoscience and Nanotechnology, Stevenson Ranch, v. 15, n. 7., p. 5424-5433, 2015. Biblioteca(s): Embrapa Meio Ambiente. |
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Registros recuperados : 38 | |
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Registro Completo
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
31/10/2014 |
Data da última atualização: |
31/10/2014 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
CLEMENTE, Z.; CASTRO, V. L. S. S. de; MOURA, M. A. M.; JONSSON, C. M.; FRACETO, L. F. |
Afiliação: |
ZAIRA CLEMENTE, IB-UNICAMP; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; MONICA ACAUI MARCONDES DE MOURA, IB-APTA; CLAUDIO MARTIN JONSSON, CNPMA; LEONARDO FERNANDES FRACETO, UNESP. |
Título: |
Toxicity assessment of TiO2 nanoparticles in zebrafish embryos underdifferent exposure conditions. |
Ano de publicação: |
2014 |
Fonte/Imprenta: |
Aquatic Toxicology, Amsterdam, v. 147, p. 129-139, 2014. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidative stress, although no clear dose-response relationship was observed. The effects of nano-TiO2 appeared to depend on both the type of formulation and the illumination condition. The findings contribute to elucidation of the factors involved in the toxicity of these nanoparticles, as well as to the establishment of protocols for risk assessments of nanotechnology. MenosAbstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidati... Mostrar Tudo |
Palavras-Chave: |
Biomarker; Dióxido de titânio; FET; Fish Embryo Test; Nanoecotoxicologia; Nanotoxicology. |
Thesagro: |
Peixe de água doce; Raio ultravioleta; Toxidez. |
Thesaurus NAL: |
Danio rerio; Ecotoxicology; Nanoparticles; Nanotechnology; oxidative stress; Toxicity; Ultraviolet radiation. |
Categoria do assunto: |
H Saúde e Patologia |
Marc: |
LEADER 02888naa a2200361 a 4500 001 1998932 005 2014-10-31 008 2014 bl uuuu u00u1 u #d 100 1 $aCLEMENTE, Z. 245 $aToxicity assessment of TiO2 nanoparticles in zebrafish embryos underdifferent exposure conditions.$h[electronic resource] 260 $c2014 520 $aAbstract: The popularity of TiO2 nanoparticles (nano-TiO2) lies in their wide range of nanotechnological applications, together with low toxicity. Meanwhile, recent studies have shown that the photocatalytic properties of this material can result in alterations in their behavior in the environment, causing effects that have not yet been fully elucidated. The objective of this study was to evaluate the toxicity of two formulations of nano-TiO2 under different illumination conditions, using an experimental model coherent with the principle of the three Rs of alternative animal experimentation (reduction, refinement, and replacement). Embryos of the fish Danio rerio were exposed for 96 h to different concentrations of nano-TiO2 in the form of anatase (TA) or an anatase/rutile mixture (TM), under either visible light or a combination of visible and ultraviolet light (UV). The acute toxicity and sublethal parameters evaluated included survival rates, malformation, hatching, equilibrium, and overall length of the larvae, together with biochemical biomarkers (specific activities of catalase (CAT), glutathione S-transferase (GST), and acid phosphatase (AP)). Both TA and TM caused accelerated hatching of the larvae. Under UV irradiation, there was greater mortality of the larvae of the groups exposed to TM, compared to those exposed to TA. Exposure to TM under UV irradiation altered the equilibrium of the larvae. Alterations in the activities of CAT and GST were indicative of oxidative stress, although no clear dose-response relationship was observed. The effects of nano-TiO2 appeared to depend on both the type of formulation and the illumination condition. The findings contribute to elucidation of the factors involved in the toxicity of these nanoparticles, as well as to the establishment of protocols for risk assessments of nanotechnology. 650 $aDanio rerio 650 $aEcotoxicology 650 $aNanoparticles 650 $aNanotechnology 650 $aoxidative stress 650 $aToxicity 650 $aUltraviolet radiation 650 $aPeixe de água doce 650 $aRaio ultravioleta 650 $aToxidez 653 $aBiomarker 653 $aDióxido de titânio 653 $aFET 653 $aFish Embryo Test 653 $aNanoecotoxicologia 653 $aNanotoxicology 700 1 $aCASTRO, V. L. S. S. de 700 1 $aMOURA, M. A. M. 700 1 $aJONSSON, C. M. 700 1 $aFRACETO, L. F. 773 $tAquatic Toxicology, Amsterdam$gv. 147, p. 129-139, 2014.
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